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The majority of alcohol rehabilitation programs in use today have a very low rate of success, because of this many people have turned to medications in order to limit or stop their drinking problem. Two types of medications are presently used in the management of alcoholics, Aversive Medications and Anticraving Medications. Using two separate drugs to lose weight can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you need to err on the side of caution and allow FDA do its job and demand some research be done so the public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies come in business to make money and that they would say anything to keep people on their own medications. Researchers found out that participants taking this drug for a year, lost weight within one month and have kept the body weight off through the entire 56 weeks of the study. Contrave is a combination of the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which are made up of multiple active ingredient, which can make them more effective and safer. Combo-pilling is the newest fad or even better the newest to come under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular could be the fact that since right now there are no long term prescription diet pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug could also raise blood pressure level and heartrate, and must not be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must not used in patients with uncontrolled high blood pressure level, in addition to by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients with a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients towards the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation. Approving a drug with this particular many potentially lethal unwanted effects is inconsistent using the mission statement in the FDA. The power in the drug manufacturing lobby is blatantly evident inside the approval of countless drugs requiring 'post-marketing' studies that are clearly significant to overall drug safety within the US.