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Using two separate drugs to lose weight can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you ought to err along the side of caution and let the FDA do its job and demand some investigation be done in order that the public is aware of the side effects and perils associated with the medications before we take them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on the medications. Researchers found that participants using this drug for the year, lost excess weight within one month and have kept the weight off through the entire 56 weeks of the study. Contrave is really a combination of the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which are made up of several active ingredient, which can make them more effective and safer. Combo-pilling may be the newest fad or also the newest to come under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular may be the fact that at the time of right now there aren't any long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug also can raise blood pressure levels and pulse rate, and must not be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and heartbeat and must 't be used in patients with uncontrolled high blood pressure levels, and also by a person with heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients having a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients on the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking. Approving a drug using this type of many potentially lethal unwanted side effects is inconsistent using the mission statement of the FDA. The power in the drug manufacturing lobby is blatantly evident inside approval of several drugs requiring 'post-marketing' studies which can be clearly significant to overall drug safety inside US.